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  1. DNA probes as epidemiological tools for surveillance of Plasmodium falciparum malaria in Thailand.

    Article - En anglais

    We have previously reported on development of a DNA probe-based method for diagnosing Plasmodium falciparum infection directly from patient blood samples.

    In the present studies, we sought to examine applicability of the method to large epidemiological surveys, comparing sensitivity, specificity, time required to obtain results, and costs with those of conventional microscopic examination.

    Results of DNA probe hybridization were also compared between laboratories in the US and Thailand, to assess transferability of the DNA probe technology.

    Five separate surveys of approximately 5000 villagers each were performed between December 1987 and June 1989 (26176 samples total).

    Mots-clés Pascal : Paludisme, Protozoose, Infection, Plasmodium falciparum, Sporozoa, Protozoa, Epidémiologie, Surveillance sanitaire, Diagnostic, Homme, Sonde moléculaire, Technique, Thaïlande, Asie, Transfert technologie

    Mots-clés Pascal anglais : Malaria, Protozoal disease, Infection, Plasmodium falciparum, Sporozoa, Protozoa, Epidemiology, Sanitary surveillance, Diagnosis, Human, Molecular probe, Technique, Thailand, Asia, Technology transfer

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0261617

    Code Inist : 002B05E02B4. Création : 199406.