Alcohol consumption and colon and rectal cancer in postmenopausal women.
The associations between alcohol and colon and rectal cancers were examined in the Iowa Women's Health Study.
In January 1986, 41837 postmenopausal women, aged 55-69, completed a questionnaire including usual alcohol intake and other information.
Through December 1990, 237 incident colon and 75 rectal cancer cases occurred.
Mantel-Haenszel age-adjusted relative risks (RR) and 95% confidence intervals (Cl) for consumers of <4.0 and >=4.0 g of alcohol per day compared to abstainers were 1.07 (0.61-1.89) and 1.27 (0.72-2.24) (P for trend=0.46) for rectal cancer.
Alcohol intake was inversely associated with distal colon cancer (RR for <4.0 and >=4.0 g of alcohol per day were 0.64 and 0.69 respectively, P for trend=0.04), which was specific to wine; however, no association was observed with proximal colon cancer (P for trend=0.94).
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Epidémiologie, Toxicité, Consommation, Ethanol, Homme, Femelle, Postménopause, Iowa, Etats Unis, Amérique du Nord, Amérique, Appareil digestif pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Epidemiology, Toxicity, Consumption, Ethanol, Human, Female, Postmenopause, Iowa, United States, North America, America, Digestive diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0261603
Code Inist : 002B03F. Création : 199406.