The associations between alcohol and colon and rectal cancers were examined in the Iowa Women's Health Study.
In January 1986, 41837 postmenopausal women, aged 55-69, completed a questionnaire including usual alcohol intake and other information.
Through December 1990, 237 incident colon and 75 rectal cancer cases occurred.
Mantel-Haenszel age-adjusted relative risks (RR) and 95% confidence intervals (Cl) for consumers of <4.0 and >=4.0 g of alcohol per day compared to abstainers were 1.07 (0.61-1.89) and 1.27 (0.72-2.24) (P for trend=0.46) for rectal cancer.
Alcohol intake was inversely associated with distal colon cancer (RR for <4.0 and >=4.0 g of alcohol per day were 0.64 and 0.69 respectively, P for trend=0.04), which was specific to wine; however, no association was observed with proximal colon cancer (P for trend=0.94).
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Epidémiologie, Toxicité, Consommation, Ethanol, Homme, Femelle, Postménopause, Iowa, Etats Unis, Amérique du Nord, Amérique, Appareil digestif pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Epidemiology, Toxicity, Consumption, Ethanol, Human, Female, Postmenopause, Iowa, United States, North America, America, Digestive diseases
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0261603
Code Inist : 002B03F. Création : 199406.