Comparison of serum lipoprotein(a) distribution and its correlates among black and white populations.
Background Epidemiological data on serum lipoprotein(a) (Lp(a)), a presumably strong risk factor for coronary artery disease in White populations, has mostly been derived, in Black populations, from small samples.
This study compares the distribution and the determinants of serum Lp(a) in Blacks and in Whites using large representative samples and the same methods in both populations.
Methods The distribution and the correlates of serum Lp(a) were investigated in population-based samples of 701 Blacks in the Seychelles and 634 Whites in Switzerland, aged 25-64 years.
Serum Lp(a) was quantified using a commercial immunoradiometric assay.
Results The distribution of serum Lp(a) was similarly skewed in both ethnic groups, but median Lp(a) concentration was about twofold higher in Blacks (210 mg/l) compared to Whites (100 mg/l).
Mots-clés Pascal : Lipoprotéine, Sérum, Etude comparative, Seychelles, Iles Océan Indien, Suisse, Europe, Race, Négroïde, Caucasoïde, Epidémiologie, Homme, Lipoprotèine A
Mots-clés Pascal anglais : Lipoprotein, Serum, Comparative study, Seychelles, Indian Ocean Islands, Switzerland, Europe, Race, Negroid, Caucasoid, Epidemiology, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0259945
Code Inist : 002B29A. Création : 199406.