This is a narrative account of the origins and development of carcinogen risk assessment in the U.S. EPA, which pioneered the field.
It began in an era of high hopes that the regulation of carcinogens in the environment would make a major reduction in the heavy public health burden of cancer.
The immediate cause for the development of carcinogen risk assessment was the need to respond to heavy criticism that the EPA was not using science in an unbiased way to defend its regulation of important pesticides as carcinogens.
The formulation of the initial assessment guidelines is described as well as the rationale behind the assessment procedures that were developed by the EPA's Carcinogen Assessment Group.
Mots-clés Pascal : Carcinogène, Toxicité, Homme, Evaluation, Risque, Etats Unis, Amérique du Nord, Amérique, Protection environnement, Stratégie, Organisme réglementation, Recommandation
Mots-clés Pascal anglais : Carcinogen, Toxicity, Human, Evaluation, Risk, United States, North America, America, Environmental protection, Strategy, Regulatory institution, Recommendation
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0231144
Code Inist : 002B04E02. Création : 199406.