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  1. HIV-1 incidence and HIV-1-associated mortality in a rural Ugandan population cohort.

    Article - En anglais

    Objective

    To determine the incidence of HIV-1 infection and HIV-1-associated mortality in a rural Ugandan population.

    Design

    A prospective cohort study.

    Methods

    A cohort consisting of the population (de jure census 4820) of a cluster of 15 villages in Masaka District, south-west Uganda was enrolled between 1484 and 1440 through a demographic and medical survey.

    The HIV-1 seroprevalence rate was 4.8% for all ages combined and 8.2% for those aged 13 years or more.

    The survey was repeated after 1 year.

    Results

    The 1-year HIV-1 incidence rate among adults was 1% [4.2 per 1000 person-years of observation; 45% confidence interval (CI), 5.5-12.4).

    A total of 84 deaths were observed.

    In adults, half of all deaths (31 out of 60) were in HIV-1-seropositive individuals.

    Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Incidence, Mortalité, Milieu rural, Ouganda, Afrique, Epidémiologie, Etude cohorte, Prospective, Homme, Immunodéficit, Immunopathologie

    Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Incidence, Mortality, Rural environment, Uganda, Africa, Epidemiology, Cohort study, Prospective, Human, Immune deficiency, Immunopathology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0216812

    Code Inist : 002B06D01. Création : 199406.