To determine the incidence of HIV-1 infection and HIV-1-associated mortality in a rural Ugandan population.
A prospective cohort study.
A cohort consisting of the population (de jure census 4820) of a cluster of 15 villages in Masaka District, south-west Uganda was enrolled between 1484 and 1440 through a demographic and medical survey.
The HIV-1 seroprevalence rate was 4.8% for all ages combined and 8.2% for those aged 13 years or more.
The survey was repeated after 1 year.
The 1-year HIV-1 incidence rate among adults was 1% [4.2 per 1000 person-years of observation; 45% confidence interval (CI), 5.5-12.4).
A total of 84 deaths were observed.
In adults, half of all deaths (31 out of 60) were in HIV-1-seropositive individuals.
Mots-clés Pascal : SIDA, Virose, Infection, Virus HIV1, Virus immunodéficience humaine, Lentivirinae, Retroviridae, Virus, Incidence, Mortalité, Milieu rural, Ouganda, Afrique, Epidémiologie, Etude cohorte, Prospective, Homme, Immunodéficit, Immunopathologie
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, HIV-1 virus, Human immunodeficiency virus, Lentivirinae, Retroviridae, Virus, Incidence, Mortality, Rural environment, Uganda, Africa, Epidemiology, Cohort study, Prospective, Human, Immune deficiency, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0216812
Code Inist : 002B06D01. Création : 199406.