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  1. Hepatitis C virus genotypes : an investigation of type-specific differences in geographic origin and disease.

    Article - En anglais

    Because of the nucleotide sequence diversity of different isolates of hepatitis C virus, it has become important to clarify whether distinct genotypes of hepatitis C virus vary with respect to pathogenicity, infectivity, response to antiviral therapy and geographic clustering.

    We assessed nucleotide sequence variability in the 5' noncoding region of hepatitis C virus, using restriction enzymes to analyze the distribution of hepatitis C virus genotypes, in 80 patients with chronic hepatitis C virus infection.

    Genotypes were correlated with demographic, clinical and histological features.

    Mots-clés Pascal : Pouvoir pathogène, Pouvoir infectant, Antiviral, Hépatite virale C, Virose, Infection, Virus hépatite C, Flaviviridae, Virus, Interféron, Traitement, Epidémiologie, Répartition géographique, Forme clinique, Homme, Génotype, Appareil digestif pathologie, Foie pathologie

    Mots-clés Pascal anglais : Pathogenicity, Infectivity, Antiviral, Viral hepatitis C, Viral disease, Infection, Hepatitis C virus, Flaviviridae, Virus, Interferon, Treatment, Epidemiology, Geographic distribution, Clinical form, Human, Genotype, Digestive diseases, Hepatic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0214628

    Code Inist : 002B05C02G. Création : 199406.