logo BDSP

Base documentaire


Fermeture du portail BDSP le 1er juillet 2019. En savoir plus...

  1. Human T-lymphotropic virus type I in Japan.

    Article - En anglais

    Adult T-cell leukaemia (ATL) was first reported in Japan, where it has a high incidence in the southwest region.

    The retrovirus human T-lymphotropic virus type I (HTLV-I) is the cause of ATL; and in ATL-endemic areas, the rate of carriage of antibodies to HTLV-I is high.

    A definite diagnosis of ATL is based on the presence of HTLV-I proviral DNA in the tumour-cell DNA.

    ATL cells originate from the CD4 subset of peripheral T cells.

    ATL shows diverse clinical features but can be divided into four subtypes-acute, chronic, smouldering, and lymphoma type.

    It is resistant to chemotherapy, and the acute and lymphoma types have a poor prognosis.

    Familial occurrence of ATL is common.

    HTLV-I infection is caused by transmission of live infected lymphocytes from mother to child, from man to woman, or by transfusion.

    Mots-clés Pascal : Hémopathie maligne, Immunopathologie, Infection, Epidémiologie, Etiopathogénie, Homme, Race, Mongoloïde, Virus HTLV1, Retroviridae, Virus, Japon, Asie

    Mots-clés Pascal anglais : Malignant hemopathy, Immunopathology, Infection, Epidemiology, Etiopathogenesis, Human, Race, Mongoloid, HTLV-I virus, Retroviridae, Virus, Japan, Asia

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0197395

    Code Inist : 002B06D01. Création : 199406.



Fermeture du portail BDSP le 1er juillet 2019

Nous avons le regret de vous informer de la fermeture du portail BDSP le 1er juillet 2019. Du 1er janvier au 30 juin 2019, le site et ses services resteront accessibles mais ne seront plus alimentés, ni mis à jour. En savoir plus...