Developmental data were abstracted from medical records on 50 trisomy 18 individuals ranging in age from 1 to 232 months and 12 trisomy 13 individuals ranging in age from 1 to 130 months.
Data on the age when trisomy 18 and trisomy 13 children achieved developmental skills were collected from a larger group of 62 trisomy 18 individuals and 14 trisomy 13 individuals whose families filled out parent questionnaires.
Developmental quotient (DQ), debned as developmental age divided by chronological age, averaged 0.18 for trisomy 18 and 0.25 for trisomy 13.
There was a dramatic drop in DQ from infancy to later childhood.
The highest DQs and the greatest variation in DQs were in the first 2-3 years of life.
Mots-clés Pascal : Chromosome D13, Chromosome E18, Trisomie, Aneuploïdie, Aberration chromosomique, Homme, Développement psychomoteur, Epidémiologie, Exploration
Mots-clés Pascal anglais : D13-Chromosome, E18-Chromosome, Trisomy, Aneuploidy, Chromosomal aberration, Human, Psychomotor development, Epidemiology, Exploration
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0191178
Code Inist : 002B23B. Création : 199406.