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  1. Is reactive airways dysfunction syndrome a variant of occupational asthma ?

    Article - En anglais

    Background

    Reactive airways dysfunction syndrome (RADS) or irritant-induced asthma is a syndrome that leaves subjects with asthma-like symptoms after one or more exposures to a high concentration of an irritant substance.

    The degree of reversibility of airway obstruction in subjects with RADS in nevertheless unknown, as is the degree of associated lesions at the airway level.

    Methods

    We compared the acute reversibility of forced expiratory volume in 1 second (FEV1) after inhalation of albuterol (200 mum) in 15 subjects with RADS (12 cases caused by chlorine inhalation) with that of 30 subjects with occupational asthma (OA) caused by various agents.

    Mots-clés Pascal : Asthme, Chlore, Composé irritant, Exposition professionnelle, Obstruction, Voie respiratoire, VEMS, Réversibilité, Etude comparative, Médecine travail, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Exploration

    Mots-clés Pascal anglais : Asthma, Chlorine, Irritant compound, Occupational exposure, Obstruction, Respiratory tract, Maximal expiratory volume per second, Reversibility, Comparative study, Occupational medicine, Human, Respiratory disease, Obstructive pulmonary disease, Exploration

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0186178

    Code Inist : 002B11B. Création : 199406.