Reactive airways dysfunction syndrome (RADS) or irritant-induced asthma is a syndrome that leaves subjects with asthma-like symptoms after one or more exposures to a high concentration of an irritant substance.
The degree of reversibility of airway obstruction in subjects with RADS in nevertheless unknown, as is the degree of associated lesions at the airway level.
We compared the acute reversibility of forced expiratory volume in 1 second (FEV1) after inhalation of albuterol (200 mum) in 15 subjects with RADS (12 cases caused by chlorine inhalation) with that of 30 subjects with occupational asthma (OA) caused by various agents.
Mots-clés Pascal : Asthme, Chlore, Composé irritant, Exposition professionnelle, Obstruction, Voie respiratoire, VEMS, Réversibilité, Etude comparative, Médecine travail, Homme, Appareil respiratoire pathologie, Bronchopneumopathie obstructive, Exploration
Mots-clés Pascal anglais : Asthma, Chlorine, Irritant compound, Occupational exposure, Obstruction, Respiratory tract, Maximal expiratory volume per second, Reversibility, Comparative study, Occupational medicine, Human, Respiratory disease, Obstructive pulmonary disease, Exploration
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0186178
Code Inist : 002B11B. Création : 199406.