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  1. Hyperchloremic acidosis during grand mal seizure lactic acidosis.

    Article - En anglais

    Objective

    To evaluate the prevalence and the mechanism of hyperchloremic acidosis component (HCIA) during lactic acidosis secondary to grand mal seizures.

    Design

    Retrospective study.

    Setting

    Medical intensive care unit in a university hospital.

    Patients

    35 patients admitted for grand mal seizures with lactic acidosis (pH<7.35, TCO2<20 mmol/l and PaCO2<8 kPa).

    Measurements

    HClA was defined by the ratio: excess anion gap/HCO3 deficit (deltaAG/deltaTCO2)<0.8. A difference in the distribution space of protons and their accompanying anion, i.e., a displacement of chloride from cells by the entering lactate, was evaluated by the ratio natremia/chloremia (Na+/Cl-).

    Mots-clés Pascal : Grand mal, Acidose métabolique, Lactique acide, Hyperchlorémie, Prévalence, Pathogénie, Homme, Elément minéral, Chlore, France, Europe, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Epilepsie, Trouble métabolisme, Trouble équilibre hydroélectrolytique, Trouble équilibre acidobasique, Epidémiologie

    Mots-clés Pascal anglais : Grand mal, Metabolic acidosis, Lactic acid, Hyperchloremia, Prevalence, Pathogenesis, Human, Inorganic element, Chlorine, France, Europe, Nervous system diseases, Central nervous system disease, Cerebral disorder, Epilepsy, Metabolic disorder, Hydroelectrolytic balance disorder, Acid base balance disorder, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0172018

    Code Inist : 002B17A03. Création : 199406.