A hospital-based case-control study was undertaken to examine the role of human papillomavirus (HPV) in the development of invasive cervical cancer in Brazil.
The study included 199 histologically confirmed incident cases and 225 age-frequency-matched controls selected from a wide range of diagnostic categories.
A polymerase chain reaction technique was used to detect HPV DNA in cervical specimens collected with spatula and brush.
HPV DNA was detected in 84% of the cases compared with 17% of controls.
Grouping HPV types 16, 18, 31 and 33, 66% of the cases were positive compared with only 6% of the controls.
Mots-clés Pascal : Tumeur maligne, Col utérus, Facteur risque, Papillomavirus humain, Papillomavirus, Papovaviridae, Virus, Etiologie, Epidémiologie, Brésil, Amérique du Sud, Amérique, Homme, Col utérus pathologie, Appareil génital femelle pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Uterine cervix, Risk factor, Human papillomavirus, Papillomavirus, Papovaviridae, Virus, Etiology, Epidemiology, Brazil, South America, America, Human, Uterine cervix diseases, Female genital diseases, Case control study
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0160137
Code Inist : 002B20C02. Création : 199406.