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  1. Comparative study of Lederle/Takeda acellular and Lederle whole-cell pertussis-component diphtheria-tetanus-pertussis vaccines in infants in Germany.

    Article - En anglais

    In preparation for a large efficacy trial in Germany, a pilot study was initiated in December 1990.

    In this study 149 infants were enrolled; with double-blind randomization 75 received Lederle/TaKeda acellular pertussis component diphtheria- tetanus-pertussis vaccine (APDT) and 74 received Lederle whole-cell pertussis component diphtheria-tetanuspertussis vaccine (DTP).

    The mean age at first dose was 3.5 months, and the second and third doses followed at 6-week intervals.

    Reactions were relatively mild with both vaccines; in general they were less frequent following APDT.

    Mots-clés Pascal : Nourrisson, Vaccination, Etude comparative, Vaccin associé, Diphtérie, Tétanos, Protéine activant ilot Langerhans, Bordetella pertussis, Immunoprotection, Evaluation performance, Homme, Bactériose, Infection, Bactérie

    Mots-clés Pascal anglais : Infant, Vaccination, Comparative study, Mixed vaccine, Diphtheria, Tetanus, Islet activating protein, Bordetella pertussis, Immunoprotection, Performance evaluation, Human, Bacteriosis, Infection, Bacteria

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0132234

    Code Inist : 002B30A03B. Création : 199406.