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  1. Urinary aflatoxin levels, hepatitis-B virus infection and hepatocellular carcinoma in Taiwan.

    Article - En anglais

    Using a urinary immunoassay to measure aflatoxin metabolites, we examined the associations between exposure to aflatoxin, chronic infection with the hepatitis-B virus (HBV) and background rates of hepatocellular carcinoma (HCC) mortality in a cross-sectional survey of 250 residents from 8 areas of Taiwan with a 4-fold variation in age-adjusted HCC mortality.

    Specimens of fasting blood and overnight urines were used to determine HBV carrier status and excretion of aflatoxin in the subjects surveyed.

    While the prevalence of hepatitis-B virus carriers showed moderate variability, there was a 500-fold range in urinary aflatoxin levels.

    Mean log-transformed levels of aflatoxin metabolites were similar in males and females and in HBV carriers and non-carriers.

    Mots-clés Pascal : Hépatome, Epithélioma, Foie, Hépatite virale B, Virose, Infection, Aflatoxine, Urine, Facteur risque, Epidémiologie, Taiwan, Asie, Homme, Appareil digestif pathologie, Foie pathologie, Tumeur maligne

    Mots-clés Pascal anglais : Liver cell carcinoma, Carcinoma, Liver, Viral hepatitis B, Viral disease, Infection, Aflatoxin, Urine, Risk factor, Epidemiology, Taiwan, Asia, Human, Digestive diseases, Hepatic disease, Malignant tumor

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0361709

    Code Inist : 002B13C01. Création : 199406.