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  1. Cigarette smoking and risk of acute leukemia : associations with morphology and cytogenetic abnormalities in bone marrow.

    Article - En anglais

    Background

    Cigarette smoking may be a risk factor for leukemia.

    No detailed biological mechanism has been proposed, but a causal link is made plausible by evidence of systemic effects of cigarette smoke and the presence in cigarette smoke of chemicals that have been associated with leukemia risk.

    Purpose

    Our purpose was to investigate the leukemia risk associated with cigarette smoking in a multicenter case-control study of acute leukemias in adults.

    Methods

    Adults aged 18-79 with newly diagnosed leukemia were contacted to participate in this epidemiologic study when they entered a clinical trial to be treated under protocols sponsored by Cancer and Leukemia Group B.

    Mots-clés Pascal : Leucémie, Aigu, Facteur risque, Tabagisme, Morphologie, Moelle osseuse, Aberration chromosomique, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Canada, Adulte, Homme, Hémopathie maligne, Etude cas témoin

    Mots-clés Pascal anglais : Leukemia, Acute, Risk factor, Tobacco smoking, Morphology, Bone marrow, Chromosomal aberration, Epidemiology, United States, North America, America, Canada, Adult, Human, Malignant hemopathy, Case control study

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0289748

    Code Inist : 002B19B. Création : 199406.