Growth of airways and air spaces in teenagers is related to sex but not to symptoms.
To determine growth patterns of the lung and airways in adolescents, we analyzed maximal expiratory flow-volume curves, closing capacity, and residual volume.
They were obtained every 6 mo for up to 7 yr in 430 boys and 125 girls (11-19 yr), of whom 143 boys and 36 girls were classified as symptomatic; symptoms were most often minor and limited to childhood.
Development of flows vs. volumes was used to investigate growth of the airways relative to lung size.
A model of isotropic growth of the airways and air spaces (J. Appl.
Physiol. 65: 822-828, 1988) was modified for increasing elastic recoil pressure with growth.
Mots-clés Pascal : Voie respiratoire, Développement, Poumon, Courbe débit volume expiratoire maximum, Volume pulmonaire résiduel, Capacité fermeture, Sexe, Etude longitudinale, Appareil respiratoire, Adolescent, Homme
Mots-clés Pascal anglais : Respiratory tract, Development, Lung, Maximum expiratory flow volume curve, Residual lung volume, Closing capacity, Sex, Follow up study, Respiratory system, Adolescent, Human
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0259443
Code Inist : 002A20B02. Création : 199406.