Pregnancies in women with systemic lupus erythematosus are recognized to result in excessive fetal morbidity and mortality.
Maternal autoantibody status may explain some of these problems.
Anti-cardiolipin antibody has been associated with recurrent pregnancy losses in some women with lupus, but the risk of these losses has not been defined.
At the University of Pittsburgh between January 1, 1979, and December 31, 1989, an unmatched case-control study design was used to determine whether patients with lupus and anti-cardiolipin antibody (81 cases) were at increased risk for adverse pregnancy outcomes in comparison with lupus patients without the antibody (174 controls).
Mots-clés Pascal : Lupus érythémateux, Systémique, Diphosphatidylglycérol, Phospholipide, Autoanticorps, Epidémiologie, Gestation pathologie, Foetus pathologie, Nouveau né pathologie, Homme, Femelle, Pennsylvanie, Etats Unis, Amérique du Nord, Amérique, Peau pathologie, Tissu conjonctif pathologie, Maladie système, Maladie autoimmune, Immunopathologie
Mots-clés Pascal anglais : Lupus erythematosus, Systemic, Diphosphatidylglycerol, Phospholipid, Autoantibody, Epidemiology, Pregnancy disorders, Fetal diseases, Newborn diseases, Human, Female, Pennsylvania, United States, North America, America, Skin disease, Connective tissue disease, Systemic disease, Autoimmune disease, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0200908
Code Inist : 002B07. Création : 199406.