Qualitative analysis of 100 consecutive computed tomographic (CT) studies of the brain in children with symptomatic-but untreated acquired immunodeficiency syndrome was performed.
After excluding children with associated medical illnesses that might confound the diagnosis of encephalopathy or alter brain structure, an abnormality of at least one of the measures of ventricular size, cortical atrophy, white matter attenuation (leukoaraiosis), or cerebral calcification was found in 86% of the patients studied.
Ventricular enlargement was the most common abnormality, followed by cortical atrophy, leukoaraiosis, and cerebral calcification.
Cerebellar atrophy was an unexpected but relatively common finding in 12% of the children.
Sixty-five percent of the children were encephalopathic at the time of evaluation.
Mots-clés Pascal : SIDA, Virose, Infection, Enfant, Homme, Exploration, Cervelet pathologie, Prévalence, Epidémiologie, Tomodensitométrie, Etats Unis, Amérique du Nord, Amérique, Hémopathie, Immunopathologie, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Radiodiagnostic
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Child, Human, Exploration, Cerebellar disease, Prevalence, Epidemiology, Computerized axial tomography, United States, North America, America, Hemopathy, Immunopathology, Nervous system diseases, Central nervous system disease, Cerebral disorder, Radiodiagnosis
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0159942
Code Inist : 002B06D01. Création : 199406.