Cancer in a young population in a dioxin-contaminated area.
An industrial accident in Seveso, Italy, in 1976, caused contamination of the residential community with 2,3,7,8-tetrachlorodibenzo-p-dioxin ITCDD).
We investigated cancer occurrence in the first post-accident decade (1977-1986) among nearly 20 000 subjects aged 0-19 years.
People who left the area were actively followed with a 99% follow-up rate.
For reported cancer cases confirmation was obtained through consultation with original medical records.
Two ovarian cancers were observed versus none expected.
A suggestive increase was seen for Hodgkin's lymphoma (relative risk [RR]=2.0; 95% confidence interval [Cl]=0.5-7.6).
Myeloid leukaemia showed a clear, but not statistically significant increase (RR=2.7; 95% Cl=0.7-11.4).
Mots-clés Pascal : Tumeur maligne, Enfant, Homme, Adolescent, Nourrisson, Toxicité, Dibenzo-p-dioxine(2,3,7,8-tétrachloro), Carcinogène, Polluant, Environnement, Hémopathie maligne, Accident, Epidémiologie, Italie, Europe, Seveso
Mots-clés Pascal anglais : Malignant tumor, Child, Human, Adolescent, Infant, Toxicity, Carcinogen, Pollutant, Environment, Malignant hemopathy, Accident, Epidemiology, Italy, Europe
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0148659
Code Inist : 002B04E02. Création : 199406.