Hodgkin's disease : the protective effect of childbearing.
Register and census data for complete cohorts of Norwegian men and women born between 1935 and 1974 were used to examine the relationship between reproductive factors and the incidence of Hodgkin's disease (HD).
Among 1.3 million men and 1.3 million women under observation, 695 male and 441 female cases of HD were diagnosed during the period of follow-up.
Our hazard model estimates showed that women, at a given age and in a given birth cohort, have an HD incidence inversely related to current parity.
A clear relationship was found only for the nodular sclerosis subtype.
In men, the risk of HD development was higher than that in childless women, and there was no parity effect.
The lower HD incidence among high-parity women could not be ascribed to their lower social status.
Mots-clés Pascal : Hodgkin maladie, Incidence, Parité, Norvège, Europe, Epidémiologie, Homme, Lymphome, Lymphoprolifératif syndrome, Hémopathie maligne
Mots-clés Pascal anglais : Hodgkin disease, Incidence, Parity, Norway, Europe, Epidemiology, Human, Lymphoma, Lymphoproliferative syndrome, Malignant hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0132670
Code Inist : 002B19B. Création : 199406.