Prevalence of antibodies to hepatitis C virus among family members of patients with chronic hepatitis C.
In this study, 108 family members of 40 chronically HCV-infected patients (19 post-transfusion and 21 sporadic), and 45 families of 16 anti-HCV-negative index cases (control group) were tested for anti-HCV antibodies.
Anti-HCV antibodies were found in 16 (14.8%) families of anti-HCV-positive index cases (15% males and 14.6% females; p=NS), with no difference between families of index cases with post-transfusion and those with sporadic HCV infection.
Out of the 16 anti-HCV positive family members, 12 (75%) had clinical and/or serological evidence of chronic liver damage.
None of the control group subjects were anti-HCV-positive (p<0.01).
Mots-clés Pascal : Hépatite virale C, Virose, Infection, Chronique, Transmission, Milieu familial, Sérologie, Epidémiologie, Prévalence, Italie, Europe, Etude familiale, Homme, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis C, Viral disease, Infection, Chronic, Transmission, Family environment, Serology, Epidemiology, Prevalence, Italy, Europe, Family study, Human, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0127211
Code Inist : 002B05C02G. Création : 199406.