The epidemiology of three serious cardiac defects a joint study between five centres.
The paper reports a joint study made by five member programs of the International Clearinghouse for Birth Defects Monitoring Systems.
Three specific heart malformations were studied, hypoplastic left heart syndrome (HLHS), transposition of the great vessels (TGV), tetralogy of Fallot, and some epidemiological characteristics were analyzed.
The prevalence at birth was estimated to be 2.0, 2.9, and 2.2 per 10,000 births, respectively.
No time trend in the prevalence at birth was observed for any one of the three malformations in the total study population.
When only isolated defects were considered (infants without major non-cardiac malformations), all three cardiac anomalies showed an increased rate in infants with low birth weight, short gestational duration and probably twinning.
Mots-clés Pascal : Hypoplasie, Ventricule gauche, Tétralogie Fallot, Transposition gros vaisseaux, Epidémiologie, Nouveau né, Homme, Prévalence, Etude multicentrique, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Cardiopathie, Maladie congénitale
Mots-clés Pascal anglais : Hypoplasia, Left ventricle, Fallot tetralogy, Transposition of the great vessels, Epidemiology, Newborn, Human, Prevalence, Multicenter study, Cardiovascular disease, Vascular disease, Heart disease, Congenital disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0127208
Code Inist : 002B12A08. Création : 199406.