Poliomyelitis remains an important public health problem in China.
Most cases anb outbreaks are associated with wild type 1 polioviruses.
To obtain an overview of type 1 poliovirus transmission in China, partial genomic sequences were compared for 24 case isolates from 12 provinces.
Because polioviruses evolve rapibly during infection of humans, the genetic relationships among isolates provide a measure of the extent of epidemiologic linkage among cases.
The observed genetic relationships were complex: six different genotypes, apparently derived from five separate endemic origins, were found.
Mots-clés Pascal : Poliovirus 1, Enterovirus, Picornaviridae, Virus, Exploration microbiologique, Répartition géographique, Transmission homme homme, Chine, Asie, Homme, Epidémiologie, Linkage, Génotype
Mots-clés Pascal anglais : Poliovirus 1, Enterovirus, Picornaviridae, Virus, Microbiological investigation, Geographic distribution, Transmission from man to man, China, Asia, Human, Epidemiology, Linkage, Genotype
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0127033
Code Inist : 002B05C02A. Création : 199406.