Presymptomatic testing for Huntington's disease : a world wide survey.
World wide data on presymptomatic testing for Huntington's disease using closely linked DNA markers show that 1479 persons at risk received completed test results up to the end of 1991.
Testing has been carried out in 19 countries, with at least 88 centres involved, and numbers have levelled off after a peak in 1990.
Only 5 ; of those at risk have been tested in six countries with the longest established programmes.
Continued monitoring of international data will be of value in assessing the spread and impact of genetic testing, not only for Huntington's disease, but for other serious genetic disorders of later life.
Mots-clés Pascal : Chorée Huntington, Homme, Dépistage, Asymptomatique, Diagnostic, Epidémiologie, Monde, Système nerveux pathologie, Système nerveux central pathologie, Encéphale pathologie, Extrapyramidal syndrome, Maladie dégénérative, Maladie héréditaire
Mots-clés Pascal anglais : Huntington disease, Human, Medical screening, Asymptomatic, Diagnosis, Epidemiology, World, Nervous system diseases, Central nervous system disease, Cerebral disorder, Extrapyramidal syndrome, Degenerative disease, Genetic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0120325
Code Inist : 002B17G. Création : 199406.