The risks of second primary cancer were analysed in 2846 patients with Hodgkin's disease treated within the British National Lymphoma Investigation during 1970-87.
The relative risk (RR) of leukaemia was signiticantly greater in women (RR=30.1; 95% confidence limits (CL) 13.0 -59.5) than in men (RR=10.9; 95% CL 4.7-21.5), and showed a significant trend of greater risk with younger age at first treatment (P<0.001).
The relative risk of solid cancers was similar between the sexes, but again significantly greater at young than at older ages of first treatment (P<0.01).
Mots-clés Pascal : Hodgkin maladie, Facteur risque, Age, Second cancer, Sexe, Stade clinique, Histologie, Splénectomie, Epidémiologie, Royaume Uni, Europe, Homme, Lymphome, Lymphoprolifératif syndrome, Hémopathie maligne, Tumeur maligne
Mots-clés Pascal anglais : Hodgkin disease, Risk factor, Age, Second cancer, Sex, Clinical stage, Histology, Splenectomy, Epidemiology, United Kingdom, Europe, Human, Lymphoma, Lymphoproliferative syndrome, Malignant hemopathy, Malignant tumor
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0110294
Code Inist : 002B04B. Création : 199406.