Newmark et al. (J Nati Cancer inst 1984;72: 1323-8) hypothesized that supplementation with calcium would decrease the concentration of bile acids in aqueous phase feces and that such a reduction would reduce the risk of malignant disease in the bowel.
A randomized trial was therefore undertaken to examine the effects of calcium supplementation on fecal biochemistry.
A total of 68 men between 40 and 60 years of age volunteered to participate after having been selected randomly from population lists in Scarborough, a city in the Toronto area, Ontario, Canada.
Participants were randomly assigned to receive a daily supplement of 3 g of calcium carbonate or a sucrose placebo for a period of 1 week.
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Epidémiologie, Homme, Fèces, Acide biliaire, Régime alimentaire enrichi, Calcium, Ontario, Canada, Amérique du Nord, Amérique, Appareil digestif pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Epidemiology, Human, Feces, Bile acid, Supplemented diet, Calcium, Ontario, Canada, North America, America, Digestive diseases
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Cote : 94-0108507
Code Inist : 002B13B01. Création : 199406.