Randomized trial of the effect of calcium supplementation on fecal risk factors for colorectal cancer.

Randomized trial of the effect of calcium supplementation on fecal risk factors for colorectal cancer.

Réf. 74401 Article - En anglais

AMERICAN JOURNAL OF EPIDEMIOLOGY, vol. 138, n° 10, 1993, pages 804-814, 67 réf., ISSN 0002-9262, USA

ALDER (R.J.) ^*, MCKEOWN-EYSSEN (G.), BRIGHT-SEE (E.)

Newmark et al. (J Nati Cancer inst 1984;72: 1323-8) hypothesized that supplementation with calcium would decrease the concentration of bile acids in aqueous phase feces and that such a reduction would reduce the risk of malignant disease in the bowel.
A randomized trial was therefore undertaken to examine the effects of calcium supplementation on fecal biochemistry.
A total of 68 men between 40 and 60 years of age volunteered to participate after having been selected randomly from population lists in Scarborough, a city in the Toronto area, Ontario, Canada.
Participants were randomly assigned to receive a daily supplement of 3 g of calcium carbonate or a sucrose placebo for a period of 1 week.

Mots-clés BDSP : Cancer, Epidémiologie, Homme, Acide biliaire, Calcium, Canada, Amérique, Appareil digestif [pathologie]

Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Epidémiologie, Homme, Fèces, Acide biliaire, Régime alimentaire enrichi, Calcium, Ontario, Canada, Amérique du Nord, Amérique, Appareil digestif pathologie

Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Epidemiology, Human, Feces, Bile acid, Supplemented diet, Calcium, Ontario, Canada, North America, America, Digestive diseases

Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique

Cote : 94-0108507
Code Inist : 002B13B01. Création : 199406.

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