Multiple sexual partners and mother-to-child transmission of HIV-1.
To investigate risk factors for mother-to-child transmission of HIV-1, particularly sexual behavior before and during pregnancy.
Design and methods
This study is part of a prospective cohort study in Butare, Rwanda, of 318 HIV-1-seropositive and 309 HIV-1-seronegative women enrolled during pregnancy and followed for a mean duration of 21 months (range, 8-34 months).
Clinical follow-up of the mother-infant pairs was performed at 6-week intervals during the first year of life and at 4-month intervals thereafter.
Detailed sexual history interviews were conducted during pregnancy and at the first postnatal visit.
Of 184 singleton infants born to HIV-1-infected mothers who survived the neonatal period, 32 (17%) children were classified as H IV-1-infected, 130 (71%) as not infected, and 22 (12%) died with indeterminate HIV-1 infection status.
Mots-clés Pascal : SIDA, Virose, Infection, Comportement sexuel, Gestation, Rwanda, Afrique, Facteur risque, Exploration immunologique, Mère, Enfant, Homme, Transmission, Epidémiologie, Hémopathie, Immunopathologie, Transmission verticale
Mots-clés Pascal anglais : AIDS, Viral disease, Infection, Sexual behavior, Pregnancy, Rwanda, Africa, Risk factor, Immunological investigation, Mother, Child, Human, Transmission, Epidemiology, Hemopathy, Immunopathology
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0108486
Code Inist : 002B06D01. Création : 199406.