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  1. Helicobacter pylori infection in Japanese patients with adenocarcinoma of the stomach.

    Article - En anglais

    To examine the association of Helicobacter pylori infection with adenocarcinoma of the stomach in Japanese patients, we studied 29 patients and 58 matched controls.

    Ascertainment of H. pylori status was based on the presence of specific IgG to H. pylori.

    For the entire group, an association of this infection with gastric adenocarcinoma was suggested but not statistically significant.

    For patients in a putatively high-risk subgroup (non-cardia tumors and age <=70 years), the association was significant.

    Assays detecting serum IgA to whole H. pylori cells and cytotoxin, IgG to cytotoxin and Hp54K (the heat-shock protein homolog) and serum neutralization of cytotoxin activity each showed clear differences between H. pylori-infected and uninfected persons in this population.

    Mots-clés Pascal : Epithélioma glandulaire, Estomac, Facteur risque, Bactériose, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bactérie, IgA, Immunoglobuline, Anticorps, Marqueur biologique, Cofacteur, Epidémiologie, Homme, Tumeur maligne, Estomac pathologie, Appareil digestif pathologie

    Mots-clés Pascal anglais : Adenocarcinoma, Stomach, Risk factor, Bacteriosis, Infection, Helicobacter pylori, Spirillaceae, Spirillales, Bacteria, IgA, Immunoglobulins, Antibody, Biological marker, Cofactor, Epidemiology, Human, Malignant tumor, Gastric disease, Digestive diseases

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0098636

    Code Inist : 002B13B01. Création : 199406.