Sero-epidemiology of hepatitis A in black South African children.
A community-based sero-epidemiological survey was undertaken to determine the age-specific prevalence rates of hepatitis a virus (HAV) infection in a representative sample of 782 urban black children aged from newborn to 13 years.
Among children aged 0-5 months, the prevalence of anti-HAV was 68,8% (95% confidence interval (CI) 60,6 -77,0%); this fell to a low of 2,5% (CI 0,1-4,9%) in those aged 6-11 months, implying the presence of maternal antibody in the first few months of life.
By the age of 2 years, 51,2% (CI 45,7-56,7%) had anti-HAV, by age 4 the prevalence had risen to 81,4% (CI 75,5-87,3%) and by age 6, the prevalence of anti-HAV was almost 100% (CI 90,5- 96,7%), reflecting the poor socio-economic and environmental conditions these children live in.
Mots-clés Pascal : Hépatite virale A, Virose, Infection, Sérologie, Prévalence, Virus hépatite A, Picornaviridae, Virus, Epidémiologie, Race, Négroïde, Enfant, Homme, République Sud Africaine, Afrique, Appareil digestif pathologie, Foie pathologie
Mots-clés Pascal anglais : Viral hepatitis A, Viral disease, Infection, Serology, Prevalence, Hepatitis A virus, Picornaviridae, Virus, Epidemiology, Race, Negroid, Child, Human, South Africa, Africa, Digestive diseases, Hepatic disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0096771
Code Inist : 002B05C02G. Création : 199406.