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  1. Association of HLA-DR14-DR52 with low responsiveness to hepatitis B vaccine in Chinese residents in Taiwan.

    Article - En anglais

    To determine the HLA-linked immune response gene that controls low responsiveness to hepatitis B surface antigen (HBsAg), HLA typing was performed in 33 initial non-responders (male:female=23:10, age 1.5-46 years) who had poor antibody response (anti-HBs<10 MIU ML-1) after four doses of plasma-devined hepatitis B vaccine.

    Of 33 initial non-responders, 26 received two additional doses of either the same vaccine (n=18) or recombinant hepatitis B vaccine (n=8) and returned for anti-HBs measurement.

    Mots-clés Pascal : Virus hépatite B, Hepadnaviridae, Virus, Vaccin, Immunodéficit, Immunoprotection, Chinois, Déterminisme génétique, Typage, Système HLA, Système histocompatibilité majeur, Locus HLA-DR, Taiwan, Asie, Réponse immune

    Mots-clés Pascal anglais : Hepatitis B virus, Hepadnaviridae, Virus, Vaccine, Immune deficiency, Immunoprotection, Chinese, Genetic inheritance, Typing, HLA-System, Major histocompatibility system, HLA-DR-Locus, Taiwan, Asia, Immune response

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0094632

    Code Inist : 002B05A02. Création : 199406.