To determine the incidence of and risk factors for adverse reactions followingthe boosters, we conducted a nationwide prospective study of persons receiving pre-exposure booster vaccination with human diploid cell rabies vaccine (HDCV).
Persons who had previously received three pre-exposure doses of HDCV and whose rabies neutralizing antibody titres were <=1:5 were enrolled in the study if they stated that they intended to receive a booster.
Of the 98 persons enrolled in the study, 40 (41 ;) were in risk groups for whom boosters are not recommended.
Three (3%) of 98 developed generalized urticaria or wheezing within 1 day of receiving boosters and three others (3%) developed urticaria 6 to 14 days after the booster.
Mots-clés Pascal : Vaccin, Rage, Virose, Infection, Facteur risque, Hypersensibilité, Allergie, Epidémiologie, Vaccination, Etats Unis, Amérique du Nord, Amérique, Toxicité, Homme, Foetus, Lignée MRC5
Mots-clés Pascal anglais : Vaccine, Rabies, Viral disease, Infection, Risk factor, Hypersensitivity, Allergy, Epidemiology, Vaccination, United States, North America, America, Toxicity, Human, Fetus
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0094626
Code Inist : 002B05A02. Création : 199406.