In August 1991, the Institute of Medicine released a report entitled Adverse Effects of Pertussis and Rubella Vaccines, wich examined, among others, the relation between immunization with whole-cell diphtheria-tetanus-pertussis (DTP) vaccine and both acute encephalopathy and chronic neurological damage.
The committee reviewed information from a wide range of both professional and lay sources and found that the evidence is consistent with a possible causal relation between DTP vaccine and acute encephalopathy, although it is insufficient to establish causality.
The range of excess risk of acute encephalopathy following DTP immunization is consistent with that estimated from the National Childhood Encephalopathy Study: 0.0 to 10.5 cases per million immunizations.
Mots-clés Pascal : Article synthèse, Risque, Vaccin, Diphtérie, Bactériose, Infection, Tétanos, Coqueluche, Aigu, Encéphalopathie, Système nerveux pathologie, Système nerveux central pathologie, Homme, Toxicité, Chronique, Trouble neurologique, Epidémiologie, Etats Unis, Amérique du Nord, Amérique
Mots-clés Pascal anglais : Review, Risk, Vaccine, Diphtheria, Bacteriosis, Infection, Tetanus, Whooping cough, Acute, Encephalopathy, Nervous system diseases, Central nervous system disease, Human, Toxicity, Chronic, Neurological disorder, Epidemiology, United States, North America, America
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0094622
Code Inist : 002B05B02B. Création : 199406.