The female/male mortality ratio among unimmunized children and children vaccinated with standard or high-titer measles vaccines was examined for all children born in the period 1985-1991 in a rural area of Senegal.
The female/male mortality ratio from 9 months to 5 years of age for unvaccinated children was 0.94 (95% confidence interval (CI) 0.75-1.19), significantly different from the ratio of 0.64 (95% CI 0.48-0.85) for recipients of the Schwarz standard measles vaccine (p=0.040).
In the 4-year period, where high-titer measles vaccines were used in the study area, the female/male mortality ratio was 1.33 (95% CI 1.00-1.78) for recipients of high-titer Edmonston-Zagreb or Schwarz vaccines compared with 0.67 (95% CI 0.42-1.07) for recipients of the Schwarz standard vaccine (p=0.013).
Mots-clés Pascal : Rougeole, Virose, Infection, Vaccination, Prévention, Mortalité, Relation dose réponse, Immunoprotection, Epidémiologie, Milieu rural, Sénégal, Afrique, Enfant, Homme, Sexe, Surveillance sanitaire
Mots-clés Pascal anglais : Measles, Viral disease, Infection, Vaccination, Prevention, Mortality, Dose activity relation, Immunoprotection, Epidemiology, Rural environment, Senegal, Africa, Child, Human, Sex, Sanitary surveillance
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0089754
Code Inist : 002B05C02C. Création : 199406.