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  1. Urinary bêta2-microglobulin concentration and mortality in a cadmium-polluted area.

    Article - En anglais

    A 9-y follow-up study of 3 178 persons who lived in a caldmium-polluted area was conducted to assess the influence of environmental exposure on long-term outcome.

    The standardized mortality ratios of the urinary bêta2-microglobulin-positive subjects (>1 000 mug/g creatinine) of both sexes were higher than those of the general Japanese population, whereas the cumulative survival curves were lower than those of the urinary bêta2-microglobulin-negative group.

    A significant association was also found between urinary bêta2-microglobulin and mortabity, using a Cox's proportional hazards model.

    Mots-clés Pascal : Cadmium, Métal lourd, Polluant, Environnement, Toxicité, Etude longitudinale, Homme, Surveillance biologique, Urine, Rein, Tube rénal, Pronostic, Marqueur biologique, Appareil urinaire pathologie, Microglobuline bêta2, Mortalité

    Mots-clés Pascal anglais : Cadmium, Heavy metal, Pollutant, Environment, Toxicity, Follow up study, Human, Biological monitoring, Urine, Kidney, Renal tubule, Prognosis, Biological marker, Urinary system disease, bêta2-Microglobulin, Mortality

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0088343

    Code Inist : 002B03M01. Création : 199406.