Childhood anemia in Africa: to transfuse or not transfuse?
Blood transfusions are an important route for HIV transmission in Africa.
To explore whether transfusions are necessary in the case management of childhood anemia, a randomized trial was performed in Ifakara, Tanzania, a holoendemic malaria region. 116 children were randomized to receive either treatment for malaria and hookworm alone or, in addition, a transfusion of whole blood which had been tested negative for antibodies against the human immunodeficiency virus.
Mean packed cell volume (PCV) at admission was 14.0% in the transfusion and 14.4% in the no transfusion group.
Children were followed up for 8 weeks with measurements of PCV at 2 days, 4 weeks and 8 weeks after study entry.
PCV was similar in both groups after 4 and 8 weeks (22.9% in the transfusion and 23.6% in the no transfusion group).
Mots-clés Pascal : Anémie, Enfant, Homme, Tanzanie, Afrique, Etude statistique, Indication, Transfusion, Sang, Aspect économique, Risque infectieux, Hémopathie
Mots-clés Pascal anglais : Anemia, Child, Human, Tanzania, Africa, Statistical study, Indication, Transfusion, Blood, Economic aspect, Infectious risk, Hemopathy
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0088257
Code Inist : 002B19A01. Création : 199406.