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  1. Natural history of idiopathic dilated cardiomyopathy : effect of referral bias and secular trend.

    Article - En anglais


    The current study was designed to determine the effect of secular trend and referral bias on the natural history of idiopathic dilated cardiomyopathy.


    In a previous study of 104 patients with idiopathic dilated caraiomyopathy conducted in a referral population at the Mayo Clinic between 1960 and 1973, the 1- and 5-year mortality rates were 31% and 64%, respectively.

    A recent study of 40 patients with idiopathic dilated cardiomyopathy conducted in a population-based cohort at the Mayo Clinic between 1975 and 1984 reported 1- and 5-year morality rates of 5% and 20%, respectively.

    We hypothesized that improvements in diagnosis and therapy have occurred since the original referral cohort was described and that these improvements have altered the apparent natural history of the disease.

    Mots-clés Pascal : Cardiomyopathie hypertrophique congestive, Homme, Idiopathique, Biais méthodologique, Méthode étude, Historique, Epidémiologie, Appareil circulatoire pathologie, Cardiopathie, Myocarde pathologie

    Mots-clés Pascal anglais : Congestive hypertrophic cardiomyopathy, Human, Idiopathic, Methodological bias, Investigation method, Case history, Epidemiology, Cardiovascular disease, Heart disease, Myocardial disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0084648

    Code Inist : 002B12A05. Création : 199406.