To investigate smoking for its association with the incidence of seropositive and seronegative rheumatoid arthritis (RA).
A cohort of adult Finns was examined by the Social Insurance Institution's Mobile Clinic in 1966-72.
The 24,445 women and 28,364 men who had neither arthritis nor a history of it at the start of the study were followed until the end of 1989 using record linkage with the Institution's population register to identify patients entitled to free antirheumatic medication.
Sufficient information was obtained on 512 incident cases of RA, of whom 119 men and 229 women were seropositive and 42 men and 122 women seronegative.
There was a close association between smoking and the incidence of seropositive RA in men.
Mots-clés Pascal : Polyarthrite rhumatoïde, Adulte, Homme, Epidémiologie, Facteur risque, Tabagisme, Etude cohorte, Etude statistique, Incidence, Finlande, Europe, Chronique, Système ostéoarticulaire pathologie, Rhumatisme inflammatoire, Immunopathologie, Maladie autoimmune
Mots-clés Pascal anglais : Rheumatoid arthritis, Adult, Human, Epidemiology, Risk factor, Tobacco smoking, Cohort study, Statistical study, Incidence, Finland, Europe, Chronic, Diseases of the osteoarticular system, Inflammatory joint disease, Immunopathology, Autoimmune disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0077237
Code Inist : 002B15D. Création : 199406.