The general objective of this study was to evaluate the risks of agranulocytosis and aplastic anemia in relation to drug use.
Other potential risk factors, including history of infectious mononucleosis, were also evaluated.
In an international population-based case-control study, cases of agranulocytosis and aplastic anemia and controls, who were patients with selected diagnoses, were identified from the same hospitals.
Information on drug use was obtained in a structured interview.
Limited information on environmental exposures and on selected items of medical history, including infectious mononucleosis, was also recorded.
The possible effects of these factors on the risk of the two blood dyscrasias were evaluated.
Mots-clés Pascal : Agranulocytose, Facteur risque, Médicament, Anémie aplasique, Toxicité, Epidémiologie, Mononucléose infectieuse, Virose, Infection, Homme, Hémopathie, Neutropénie, Leucopénie
Mots-clés Pascal anglais : Agranulocytosis, Risk factor, Drug, Aplastic anemia, Toxicity, Epidemiology, Infectious mononucleosis, Viral disease, Infection, Human, Hemopathy, Neutropenia, Leukopenia
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0077232
Code Inist : 002B19D. Création : 199406.