To evaluate the association of plasma protein C levels with constitutional, socioeconomic, life-style and biochemical factors important in cardiovascular diseases, we measured protein C levels in 12,290 middle aged (45-64 years) subjects participating in the ARIC study.
Protein C levels had a normal distribution with a mean value of 3.17 mug/ml.
They were higher in women than men and in whites than blacks; higher in postmenopausal women and further increased by hormonal supplements.
The age influence was inconsistent and was considered to be inconsequential.
Protein C levels were positively correlated with body mass index, LDLcholesterol, HDL-cholesterol, and triglycerides and negatively associated with cigarette smoking.
Mots-clés Pascal : Athérosclérose, Facteur risque, Protéine C, Anticoagulant, Plasma sanguin, Corrélation, Indice masse corporelle, Cholestérol HDL, Cholestérol LDL, Triglycéride, Epidémiologie, Etats Unis, Amérique du Nord, Amérique, Age mûr, Adulte, Homme, Appareil circulatoire pathologie, Vaisseau sanguin pathologie, Lipide
Mots-clés Pascal anglais : Atherosclerosis, Risk factor, Protein C, Anticoagulant, Blood plasma, Correlation, Body mass index, Cholesterol HDL, Cholesterol LDL, Triglyceride, Epidemiology, United States, North America, America, Middle age, Adult, Human, Cardiovascular disease, Vascular disease, Lipids
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0061838
Code Inist : 002B12B01. Création : 199406.