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  1. Decline in hepatitis B infection in sickle cell anaemia and bêta thalassaemia major.

    Article - En anglais

    Seventy five Saudi children, 55 with sickle cell anaemia and 20 with bêta thalassaemia major, who were negative for all hepatitis B virus (HBV) markers five years ago were recently investigated for exposure to HBV and hepatitis C virus (HCV) infection.

    Of the 55 patients with sickle cell anaemia and 20 with bêta thalassaemia major, 20 and five patients respectively had been vaccinated against HBV earlier and all of them still had protective antibody (anti-HBs 42-96 IU) 3-5 years after vaccination and there was no vaccine failure.

    Among the non-vaccinated children the exposure rates to HBV were 14.3% among those with sickle cell anaemia and 26.7% among those with bêta thalassaemia and this was not statistically significant when compared with the exposure rate to HBV among the general paediatric population (20. 1%).

    Mots-clés Pascal : Hépatite virale B, Virose, Infection, Enfant, Homme, Association, Thalassémie bêta, Arabie Saoudite, Asie, Epidémiologie, Anémie hématie falciforme, Prévalence, Hémopathie, Anémie hémolytique, Hémoglobinopathie, Maladie héréditaire

    Mots-clés Pascal anglais : Viral hepatitis B, Viral disease, Infection, Child, Human, Association, bêta-Thalassemia, Saudi Arabia, Asia, Epidemiology, Sickle cell anemia, Prevalence, Hemopathy, Hemolytic anemia, Hemoglobinopathy, Genetic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0061779

    Code Inist : 002B05C02G. Création : 199406.