Seroepidemiological surveys were conducted to determine the frequency and distribution of haemorrhagic fever virus (HFV) activity in the Central African Republic.
Human serum specimens (4295) were collected from 5 ecologically distinct zones.
Serological evidence of HFV activity was found in all the zones.
The filovirus antibody prevalence (24.4%, 1051/4295) was greater than the combined prevalence for Lassa virus, Rift Valley fever virus and Crimean-Congo HFV antibody (1.1%, 45/4295; P<0.01).
Evidence of filovirus activity was found in all zones: 21.3% (914/4295) of the population were seropositive for Ebola virus antibody while only 3.2% (137/4295) were seroreactive with Marburg viral antigens.
Mots-clés Pascal : Fièvre hémorragique, Arbovirose, Virose, Infection, Centrafrique, Afrique, Sérologie, Exploration immunologique, Anticorps, Epidémiologie, Répartition géographique, Prévalence, Homme
Mots-clés Pascal anglais : Hemorrhagic fever, Arbovirus disease, Viral disease, Infection, Central African Republic, Africa, Serology, Immunological investigation, Antibody, Epidemiology, Geographic distribution, Prevalence, Human
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0055523
Code Inist : 002B05C02J. Création : 199406.