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  1. haemorrhagic fever virus activity in equatorial Africa : distribution and prevalence of filovirus reactive antibody in the Central African Republic.

    Article - En anglais

    Seroepidemiological surveys were conducted to determine the frequency and distribution of haemorrhagic fever virus (HFV) activity in the Central African Republic.

    Human serum specimens (4295) were collected from 5 ecologically distinct zones.

    Serological evidence of HFV activity was found in all the zones.

    The filovirus antibody prevalence (24.4%, 1051/4295) was greater than the combined prevalence for Lassa virus, Rift Valley fever virus and Crimean-Congo HFV antibody (1.1%, 45/4295; P<0.01).

    Evidence of filovirus activity was found in all zones: 21.3% (914/4295) of the population were seropositive for Ebola virus antibody while only 3.2% (137/4295) were seroreactive with Marburg viral antigens.

    Mots-clés Pascal : Fièvre hémorragique, Arbovirose, Virose, Infection, Centrafrique, Afrique, Sérologie, Exploration immunologique, Anticorps, Epidémiologie, Répartition géographique, Prévalence, Homme

    Mots-clés Pascal anglais : Hemorrhagic fever, Arbovirus disease, Viral disease, Infection, Central African Republic, Africa, Serology, Immunological investigation, Antibody, Epidemiology, Geographic distribution, Prevalence, Human

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0055523

    Code Inist : 002B05C02J. Création : 199406.