An association between adenomatous polyps of the large bowel and colorectal cancer has been reported, in the absence, however, of population-based estimates of risk.
Subjects with histologically confirmed first diagnosis of large-bowel polyps notified to the population-based Cancer Registry of the Swiss Canton of Vaud (about 600,000 inhabitants) during the calendar period 1989-1990 were actively followed up to the end of 1990 for the subsequent occurrence of malignant neoplasms.
Among 2,496 individuals with intestinal polyps, followed for a total of 10,310 person-years at risk (6,201 among males and 4,109 among females), 150 malignant neoplasms were registered versus 152 expected.
Thus, the standardized incidence ratio (SIR) for all cancers combined was 0.99.
Mots-clés Pascal : Tumeur maligne, Côlon, Rectum, Facteur risque, Incidence, Suisse, Europe, Polype adénomateux, Epidémiologie, Homme, Côlon pathologie, Rectum pathologie, Intestin pathologie, Appareil digestif pathologie
Mots-clés Pascal anglais : Malignant tumor, Colon, Rectum, Risk factor, Incidence, Switzerland, Europe, Adenomatous polyp, Epidemiology, Human, Colonic disease, Rectal disease, Intestinal disease, Digestive diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0047442
Code Inist : 002B13B01. Création : 199406.