A hospital-based retrospective cohort study of benign breast disease (BBD) as a risk factor of future breast cancer (BC) development was conducted.
Four hundred and twenty-eight patients with biopsied BBD were followed-up for a median period of 8 years, together with age-matched women with normal breasts (normal control) and BC patients (cancer control), at the ratio of 1:2:2. Twenty-one breast cancers developed, 7 in the cases, 4 in the normal controls, and 10 in the BC controls, showing the relative risk (RR) with 95% confidence intervals (CI) to be 3.5 (1.03-11.9) in the cases with respect to the normal controls.
The RR of the cases is not lower than that of contralateral breast cancer incidence.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Mastopathie bénigne, Epidémiologie, Japon, Asie, Tumeur bénigne, Homme, Glande mammaire pathologie
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Benign mastopathy, Epidemiology, Japan, Asia, Benign neoplasm, Human, Mammary gland diseases
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0044622
Code Inist : 002B20E02. Création : 199406.