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  1. Differences in time from HIV seroconversion to CD4+ lymphocyte end-points and AIDS in cohorts of homosexual men.

    Article - En anglais


    To evaluate the decline in CD4+ counts in relation to the incidence of AIDS in different cohorts of homosexual men and to quantify possible consequences of laboratory variation in CD4+ measurement.


    Our study includes 403 men with well documented dates of HIV seroconversion originating from five cohort studies among homosexual men.

    Differences in time from HIV seroconversion to the first CD4+ count dropping <500 or 200x106/l and to AIDS were evaluated using Kaplan-Meier survival analyses.


    We found considerable differences between cohorts in CD4+ depletion, but not in the incidence of AIDS (1987 definition).

    Mots-clés Pascal : Homosexualité, SIDA, Virose, Infection, Maladie sexuellement transmissible, Mâle, Lymphocyte T, Homme, Hémogramme, Courbe survie, Incidence, Evolution, Epidémiologie, Pays Bas, Europe, Hémopathie, Immunopathologie, Antigène CD4, Séroconversion

    Mots-clés Pascal anglais : Homosexuality, AIDS, Viral disease, Infection, Sexually transmitted disease, Male, T-Lymphocyte, Human, Blood cell count, Survival curve, Incidence, Evolution, Epidemiology, Netherlands, Europe, Hemopathy, Immunopathology, Seroconversion

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0039570

    Code Inist : 002B06D01. Création : 199406.