Nonocular chlamydia infection and risk of ocular reinfection after mass treatment in a trachoma hyperendemic area.
The presence of nasal discharge on a child's face increases the risk of active trachoma, suggesting that Chlamydia trachomatis in nasal secretions may be a possible source of ocular reinfection.
The prevalence of chlamydia in nasal secretions and the risk of reinfection after mass treatment was investigated in a hyperendemic area of Tanzania.
In one village a total of 232 children aged 1 to 7 years were followed before and after mass treatment.
Clinical trachoma, and microbiologic evidence of chlamydia, were assessed at baseline, 2 and 4 weeks into mass treatment, and 4 weeks after treatment stopped.
The presence of chlamydia in ocular and nasal secretions was determined by polymerase chain reaction-enzyme immunoassay techniques.
Mots-clés Pascal : Trachome, Chlamydiose, Bactériose, Infection, Réinfection, Frottis nasal, Culture microorganisme, Facteur risque, Endémie, Prévalence, Epidémiologie, Prévention, Tanzanie, Afrique, Enfant, Homme, Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bactérie, Oeil pathologie, Conjonctive pathologie
Mots-clés Pascal anglais : Trachoma, Chlamydiosis, Bacteriosis, Infection, Reinfection, Nasal smear, Microorganism culture, Risk factor, Endemy, Prevalence, Epidemiology, Prevention, Tanzania, Africa, Child, Human, Chlamydia trachomatis, Chlamydiaceae, Chlamydiales, Bacteria, Eye disease, Conjunctiva disease
Notice produite par :
Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0036619
Code Inist : 002B05B02A. Création : 199406.