To assess the relation between oral contraceptive (OC) use and breast cancer, we analysed data from a case-control study conducted in Northern Italy between 1983 and 1991 on 2,309 cases below age 60 and 1,928 controls admitted to hospital for acute diseases unrelated to OC use and to any of the known or potential risk factors for breast cancer.
OC use was reported by 16% of cases and 14% of controls.
The multivariate relative risk (RR) for ever vs never use of combination OC was 1.2 (95% confidence interval (CI) 1.0-1.4).
However, there was no trend in risk with duration.
The RR was elevated for very short use, but declined to 0.8 (95% CI=0.5-1.0) for five or more years'use.
Mots-clés Pascal : Tumeur maligne, Glande mammaire, Facteur risque, Contraceptif, Voie orale, Epidémiologie, Italie, Europe, Nord, Homme, Glande mammaire pathologie, Etude cas témoin
Mots-clés Pascal anglais : Malignant tumor, Mammary gland, Risk factor, Contraceptive, Oral administration, Epidemiology, Italy, Europe, North, Human, Mammary gland diseases, Case control study
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Inist-CNRS - Institut de l'Information Scientifique et Technique
Cote : 94-0036469
Code Inist : 002B20E02. Création : 199406.