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  1. Sodium-lithium countertransport genotype and the probability of hypertension in adults.

    Article - En anglais

    The objective of the present study was to determine whether information about a biometrically inferred single gene with large effects on erythrocyte sodium-lithium countertransport is useful in predicting the probability of having hypertension.

    We used multivariate logistic regression to model the relationship between the probability of having hypertension and predictor traits in a sample of 382 unrelated adult women and 347 unrelated adult men from Rochester, Minn.

    First, we identified a set of demographic, biochemical, and physiological predictors.

    Second, we analyzed whether the relationship between the probability of having hypertension and the identified predictor traits was heterogeneous between the biometrically inferred single locus genotypes with large effects on sodium-lithium countertransport level.

    Mots-clés Pascal : Hypertension artérielle, Adulte, Homme, Facteur risque, Pathogénie, Déterminisme génétique, Transport ion, Sodium, Lithium, Génotype, Régression logistique, Modèle, Etude statistique, Epidémiologie, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Hypertension, Adult, Human, Risk factor, Pathogenesis, Genetic inheritance, Ion transport, Sodium, Lithium, Genotype, Logistic regression, Models, Statistical study, Epidemiology, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0026550

    Code Inist : 002B12B05B. Création : 199406.