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  1. Feasibility and efficacy of sodium reduction in the trials of hypertension prevention, phase I.

    Article - En anglais

    Phase I of the Trials of Hypertension Prevention was a multicenter, randomized trial of the feasibility and efficacy of seven nonpharmacologic interventions, including sodium reduction, in lowering blood pressure in 30- to 54-year-old individuals with a diastolic blood pressure of 80 to 89 mm Hg.

    Six centers tested an intervention designed to reduce dietary sodium to 80 mmol (1800 mg)/24 h with a total of 327 active intervention and 417 control subjects.

    The intervention consisted of eight group and two one-to-one meetings during the first 3 months, followed by less-intensive counseling and support for the duration of the study.

    The mean net decrease in sodium excretion was 43.9 mmol/24 h at 18 months.

    Women had lower sodium intake at baseline and were therefore more likely to decrease to less than 80 mmol/24 h.

    Mots-clés Pascal : Hypertension artérielle, Homme, Femelle, Négroïde, Prévention, Etude multicentrique, Efficacité traitement, Faisabilité, Régime alimentaire restrictif, Sodium, Essai clinique, Etats Unis, Amérique du Nord, Amérique, Appareil circulatoire pathologie

    Mots-clés Pascal anglais : Hypertension, Human, Female, Negroid, Prevention, Multicenter study, Treatment efficiency, Feasibility, Restricted diet, Sodium, Clinical trial, United States, North America, America, Cardiovascular disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0026543

    Code Inist : 002B12B05B. Création : 199406.