logo BDSP

Base documentaire


  1. Characterization of ceftriaxone-resistant enterobacteriaceae : a multicentre study in 26 French hospitals.

    Article - En anglais

    During a multicentre study performed in 26 French hospitals, 287 (3-2%) of 9038 Enterobacteriaceae isolated, mainly Enterobacter spp., Serratia spp., Citrobacter spp. and Klebsiella spp. were classified as ceftriaxone resistant on the basis of an MIC>4 mg/L or the presence of an extended-spectrum bêta-lactamase.

    Extended-spectrum bêta-lactamase was present mainly in Klebsiella pneumoniae (65 strains, 10-2%) and very rarely in Escherichia coli, Proteus mirabilis, Klebsiella oxytoca, Citrobacter spp. and Enterobacter spp.

    The extended-spectrum bêta-lactamases conferred low-level resistance to ceftriaxone in nearly 60% of the strains harbouring them, emphasizing the need for routine testing for the presence of these enzymes.

    Mots-clés Pascal : Ceftriaxone, Céphalosporine dérivé, Antibiotique, Antibactérien, Escherichia coli, Enterobacteriaceae, Bactérie, Proteus mirabilis, Enterobacter, Klebsiella oxytoca, Citrobacter, bêta-Lactamase, Hydrolases, Enzyme, Résistance, Klebsiella pneumoniae, Etude multicentrique, Milieu hospitalier, France, Europe, Epidémiologie

    Mots-clés Pascal anglais : Cephalosporin derivatives, Antibiotic, Antibacterial agent, Escherichia coli, Enterobacteriaceae, Bacteria, Proteus mirabilis, Enterobacter, Klebsiella oxytoca, Citrobacter, bêta-Lactamase, Hydrolases, Enzyme, Resistance, Klebsiella pneumoniae, Multicenter study, Hospital environment, France, Europe, Epidemiology

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0023443

    Code Inist : 002B02S02. Création : 199406.