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  1. Time-dependent variability in repeated measurments of cholesterol levels : clinical implications for risk misclassification and intervention monitoring.

    Article - En anglais

    Intraindividual variabiIity (IIV) in total cholesterol levels based on measurements taken 1 week apart is compared with an estimate based on measurements taken 2 years apart.

    Single-subject 95% confidence intervals around the mean of two repeated measurements were Xi+-21 and +-28 mg/dl, respectively, and Xi+-30 and +-40 mg/dl for a single measurement.

    Comparing these results with published estimates over varying time intervals shows a trend of decreasing IIV with shorter intervals, suggesting that confidence interval widths based on short-term repeated measurements and those based on longer-term repeated measurements may differ more than previously assumed.

    Mots-clés Pascal : Cholestérolémie, Cholestérol, Comparaison intraindividuelle, Homme, Epidémiologie, Simulation ordinateur, Analyse statistique, Erreur, Méthodologie, Biais

    Mots-clés Pascal anglais : Cholesterolemia, Cholesterol, Intraindividual comparison, Human, Epidemiology, Computer simulation, Statistical analysis, Error, Methodology, Bias

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0021283

    Code Inist : 002B30A01A1. Création : 199406.