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  1. Epidemiological and clinical study of sickle cell disease in France, French Guiana and Algeria.

    Article - En anglais

    The main clinical and haematological features of sickle cell patients were compared in 618 French, 50 Guianese and 87 Algerian patients.

    In homozygous sickle cell patients, the proportion of icteric subjects rises with age in all centres; the prevalence of splenomegaly reaches a peak in children from 1 to 5 years and then decreases; jaundice and splenomegaly are more often noted in Algerian and Guianese than French patients.

    The prevalence of painful crisis is comparable in the 3 centres.

    In 465 French SS children, having a mean age of 7.3+-5.9 years, the prevalence of a past history of meningitis is 7.3%, of septicaemia 4.1% of osteomyelitis 8.8%. These percentages do not differ significantly between countries.

    Mots-clés Pascal : Anémie hématie falciforme, Epidémiologie, Symptomatologie, Hémogramme, Complication, Etude comparative, France, Europe, Guyane Française, Amérique du Sud, Amérique, Algérie, Afrique, Homme, Hémopathie, Anémie hémolytique, Hémoglobinopathie, Maladie héréditaire

    Mots-clés Pascal anglais : Sickle cell anemia, Epidemiology, Symptomatology, Blood cell count, Complication, Comparative study, France, Europe, French Guiana, South America, America, Algeria, Africa, Human, Hemopathy, Hemolytic anemia, Hemoglobinopathy, Genetic disease

    Logo du centre Notice produite par :
    Inist-CNRS - Institut de l'Information Scientifique et Technique

    Cote : 94-0006074

    Code Inist : 002B19A01. Création : 199406.